The U.S. Department of Energy (DOE) has announced collaboration agreements with 24 organizations to advance the Genesis Mission, a national initiative aimed at leveraging artificial intelligence (AI) for scientific discovery, national security, and energy innovation. This move follows President Trump’s Executive Order on removing barriers to American leadership in AI and his America’s AI Action Plan, which seeks to reduce reliance on foreign sources and promote domestic innovation.
A meeting at the White House brought together industry representatives, Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy. The event marked the start of public-private partnerships focused on developing scalable national infrastructure for AI research.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The 24 organizations involved have either responded to a DOE request for information or are engaged in projects with DOE or its National Laboratories related to the Genesis Mission. Products developed under this mission are intended to be architecture-agnostic.
Participating organizations include Accenture; AMD; Anthropic; Armada; Amazon Web Services; Cerebras; CoreWeave; Dell; DrivenData; Google; Groq; Hewlett Packard Enterprise; IBM; Intel; Microsoft; NVIDIA; OpenAI; Oracle; Periodic Labs; Palantir; Project Prometheus; Radical AI; xAI; XPRIZE.
DOE has indicated plans for further engagement with private sector partners as well as academic institutions and philanthropic groups in order to expand participation in the mission. The department continues to accept submissions through open requests for information (RFIs), with deadlines set in January 2026.
More details about ongoing opportunities can be found at www.genesis.energy.gov.
